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The purpose of this multi-center observational investigation is to study the natural course of nonalcoholic fatty liver (NAFL) disease with a goal of identifying whether certain changes in lifestyle, diet, or other treatments can affect its progression. NAFL is the storage of fat in the liver, and there are presently are no approved drugs for treatment of this condition. A potentially serious form of the disease, nonalcoholic steatohepatitis (NASH), includes irritation or inflammation of the liver due to fat. This research study collects information and medical samples and is not prescriptive.
Patients of both genders, ages 6 and older, who are being managed or treated for NAFL or NASH are eligible.
Males and Females: Ages 6 and older
Participants’ past and future medical record information, including test results, information about their NAFL/NASH progression and any other health conditions, will be collected and sent to the study sponsor to be added to the database with identification redacted to maintain confidentiality. Over the course of the study, participants will complete questionnaires during annual clinic visits for management of their liver disease at Children’s Hospital of Pittsburgh of UPMC. Optionally, participants may elect to have blood samples added to the study biorepository for analysis.
Duration: Up to 5 years
TARGET PharmaSolutions, Inc.
Study Description at National Institutes of Health
Patrick McKiernan, MD
For more information about the study or enrollment, please contact:
Clinical Research Nurse Coordinator Lori Haberstroh, RN, BSN
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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