Gastroenterology Clinical Studies

Some of the many research opportunities available in Gastroenterology are listed below. Select a study to review a brief description and requirements. Parents or guardians of children who might be eligible are encouraged to inquire about enrollment. Contact information is listed at the end of each study.

Thank you for exploring these opportunities and helping us to find cures and prevent childhood disease.

Clinical Studies


Alpha-1 Antitrypsin Deficiency Study – Phase II

A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1-Antitrypsin Deficiency Read more

Colon Cleansing with Prepopik Before Colonoscopy – Phases I & II

Study Comparing the Safety and Efficacy of Prepopik versus Polyethylene Glycol Preparation in Children Read more

Constipation Treatment with Lubiprostone – Phase III

Study of Lubiprostone in Pediatric Patients with Functional Constipation Read more

Crohn’s Disease - Risk and Microbial Marker Study

Risk Stratification and Identification of Immunogenetic and Microbial Markers of Rapid Disease Progression in Children with Crohn’s Disease Read more

Crohn’s Disease and Sleep Disturbance Study – Phase IV

Treating Disrupted Sleep in Individuals with Inflammatory Bowel Disease: A Novel Adjunctive Therapy for Chronic Inflammatory Illness Read more

Crohn's Disease Treatment using Blood Stem Cells – Phase I/II

Autologous Stem Cell Transplantation with CD34 Selected Peripheral Blood Stem Cells (PBSC) in Pediatric and Young Adult Patients with Severe Crohn's Disease Read more

ICARE Research Registry

Intestinal Care and Rehabilitation Center Database Read more

Inflammatory Bowel Disease and Biopsychosocial Effects

Understanding the Biopsychosocial Underpinnings of Abdominal Pain in Inflammatory Bowel Disease Read more

Pancreatitis INSPPIRE Registry

A Study of Acute Recurrent and Chronic Pancreatitis in Children by the International Study Group of Pediatric Pancreatitis In Search of a Cure (INSPPIRE) Read more

Pediatric IBD Registry

Understanding the Biopsychosocial Underpinnings of Abdominal Pain in Inflammatory Bowel Disease Read more

TPN-Related Cholestasis Treatment with Omegaven - Phase II

Compassionate Use of Omegaven in the Treatment of Parenteral Nutrition-Associated Hepatic Injury Read more

Ulcerative Colitis PROTECT Study – Phase IV

Predicting Response to Standardized Pediatric Colitis Therapy: The PROTECT Study Read more

Mark Lowe, MD, PhD

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Feras Alissa, MD

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David Keljo, MD, PhD

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David Perlmutter, MD

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Robert Squires, MD

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Eva Szigethy, MD, PhD

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