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The purpose of this multicenter study is to compare pediatric patient experiences with Prepopik® versus polyethylene glycol (PEG) for overall colon cleansing in preparation for colonoscopy. Prepopik, which has been approved for use in adults and is being investigated for use with pediatric patients, may be easier for patients because it requires a lower consumption of prep solution than the current standard of care.
Subject to certain exclusion criteria, boys and girls aged 9 to 16 years, who are being scheduled to undergo elective colonoscopy, are eligible.
Boys: 9 to 16 years old
Girls: 9 to 16 years old
After an initial screening visit that will include a physical examination, blood and urine sampling, participants will be randomly assigned to take either PEG or a prescribed dosage of Prepopik in preparation for their colonoscopies. Participants involved in the pharmacokinetic testing portion of the study, which requires extra blood draws, will be required to spend the night before colonoscopy in Children’s Hospital of Pittsburgh of UPMC.
Visits: 5, including colonoscopy and telephone follow-up
Duration: Approximately 1 month
Ferring International Center U.S., Inc.
Study Description at National Institutes of Health
Dale King, MD
For more information about the study or enrollment, please contact:
Kathleen Calabro RN, BSN
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
Children’s Hospital of Pittsburgh of UPMC
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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