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This study tests the relationship between the common occurrence of otitis media in infants and children with palatal clefts and the function of the Eustachian tubes. It is believed that the otitis media in cleft palate infants and children is caused by poor Eustachian tube function, which in turn is caused by anatomic problems in the muscles that open the tube. Otitis media is characterized by fluid in the middle ear, which can cause hearing loss.
Children from birth to 24 months with cleft palate may be eligible to enter this study.
Boys: Up to 24 months
Girls: Up to 24 months
Children enrolled in the program will have Eustachian tube function tests prior to and after their cleft palate repair surgery and annually thereafter through age 18. Tests will include ear, nose, and throat examinations, tympanometry, Eustachian tube function testing, and, at age 5 or 6, cephalometric x-rays.
Visits: Up to 18
Duration: Up to 18 years, depending on age at enrollment
National Institute on Deafness and Other Communication Disorders
Study description at the National Institutes of Health
Cuneyt Alper, MD
For information, please contact:
Jim Seroky, MA
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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