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Children's Hospital is ranked One of America's Best Children's Hospitals.
This study is being done to evaluate the osteogenic or bone-forming potential of certain cell types. It is hoped that, in the future, tissue can be engineered to slow down the fusion or closure of the bone and reduce the amount of surgery needed as the skull and the brain grows in craniosynostosis, a skull deformity caused by the premature fusion of skull bones during infancy causing problems with brain and skull growth.
Children of both genders, ages 2 months to 18 years and who are scheduled to undergo surgery for craniosynostosis, will be eligible for inclusion in this program.
Boys: 2 months to 18 years
Girls: 2 months to 18 years
During reconstructive surgery for craniosynostosis, surgeons will collect a very small tissue sample from the side of the participant’s head, such as bone tissue that would normally be discarded during, as well as muscle and fat – combined about the size of a pencil eraser.
Visits: None beyond standard care for craniosynostosis
Duration: Not applicable
Study description at National Institutes of Health
Joseph E. Losee, MD, FACS, FAAP
To get started, please contact:
Jennifer Szczepaniak, BS
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
Children’s Hospital of Pittsburgh of UPMC
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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