Life-Threatening Event Study

Clinical Evaluation of Children Presenting with an Apparent Life-Threatening Event

Protocol Description

This study examines the causes of apparent life-threatening events (ALTE) and evaluates usefulness of certain blood tests and x-rays are for determining the cause. An ALTE occurs when a child stops breathing, turns colors and sometimes even goes limp. Parents often fear the child has died, but ALTE events are brief and the child normally recovers.

Eligibility Criteria

Boys and girls less than 2 years of age, both those who present with an ALTE, and – for the control group – those who do not.
Boys: Under age 2
Girls: Under age 2


Blood testing to measure iron, certain proteins and carbon monoxide levels will be done as well as an EKG. For patients who experienced an ALTE, additional tests, including a chest x-ray will be done. Researchers will follow-up with a phone call to the parent/guardian at 6 months and 1 year after the initial testing.
Visits: 1
Duration: 1 year

Status: Open for Enrollment

Source(s) of Support

Children’s Hospital of Pittsburgh of UMPC

Primary Investigator

Raymond Pitetti, MD, MPH

Contact Information

To get started, please contact:
Raymond Pitetti, MD, MPH