Antonio J. and Janet Palumbo Cystic Fibrosis Center (CF Center)

The Antonio J. and Janet Palumbo Cystic Fibrosis Center (CF Center) at UPMC Children's Hospital of Pittsburgh is dedicated to providing state-of-the-art care to patients and families with cystic fibrosis, education for health care professionals, and conducting clinical and basic research in cystic fibrosis. The program is accredited by the Cystic Fibrosis Foundation for clinical care and research. Based on consistently good patient outcomes, our CF Center recently was selected as a benchmarking site, from which other programs could learn from our practices.

The pediatric program cares for approximately 280 patients, and nearly 200 patients are seen in the adult program. Pediatric patients are seen in any of four locations (including the main hospital in Lawrenceville, Children's North, Children's South, and Children's East). Our team includes board-certified pediatric pulmonologists, registered dietitians, nurses, social workers, and respiratory therapists, as well as administrative support staff. Our extended team includes representatives from gastroenterology, endocrinology, and medical genetics. A pediatric pulmonologist experienced in cystic fibrosis is available 24 hours a day.

Our multidisciplinary clinical services include evaluation, diagnosis, and treatment, including emphasis on promoting normal growth and development, slowing the progression of the illness, preventing and treating complications, and helping the family integrate even the most complex care regimens into their daily lives.

Rachel, a patient of the Antonio J. and Janet Palumbo Cystic Fibrosis Center at Children’s Hospital, is a student at Johns Hopkins University.

Education and Training Program

Training tomorrow's pediatric pulmonologists is an important part of the mission of the Cystic Fibrosis Center as part of the Division of Pediatric Pulmonary Medicine. The division takes full advantage of its strengths to provide educational opportunities that are second to none, including a fellowship program that offers comprehensive training in both the clinical and research aspects of pulmonary medicine.

Learn more about our Pulmonology Fellowship program.

A Leader in Pediatric Medicine

UPMC Children’s Hospital is a recognized leader in pediatric medicine. Quality patient care and advanced research consistently place Children’s among the nation's top pediatric hospitals as reported by U.S. News & World Report. In May 2009, Children's relocated to its new, state-of-the-art campus, which includes a new hospital and the 300,000-square-foot John G. Rangos Sr. Research Center.

Learn more about Children's Hospital campus.

Read "For 13-year-old, Robert Morris lacrosse teammates are 'all my older brothers'" (Pittsburgh Post-Gazette article).

Pediatric Doctors

Adult Doctors


Clinical Studies

  • Antonio J. and Janet Palumbo Cystic Fibrosis Center (CF Center)

    UPMC Children's Hospital of Pittsburgh
    4401 Penn Avenue
    Floor 3
    Pittsburgh, PA 15224
  • Cystic Fibrosis CFTR Therapy Outcomes Analysis: The CHEC-SC Cohort Study

    Characterizing CFTR Modulated Changes in Sweat Chloride and their Association with Clinical Outcomes

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    Cystic Fibrosis MRSA Lung-Infection Treatment with AeroVanc – Phase III

    Study of AeroVanc for the Treatment of Persistent Methicillin-Resistant Staphylococcus aureus Lung Infection in Cystic Fibrosis Patients

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    Cystic Fibrosis Patient Registry

    Participation in the Cystic Fibrosis Patient Registry

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    Cystic Fibrosis Therapy Using Saline Hypertonic: The SHIP-CT Study – Phase II/III

    Saline Hypertonic in Preschoolers With Cystic Fibrosis and Lung Structure as Measured by Computed Tomography

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    Cystic Fibrosis Treatment with LAU-7b: The APPLAUD Study – Phase II

    Study of the Efficacy and Safety of LAU-7b in the Treatment of Cystic Fibrosis in Adults

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    Cystic Fibrosis Treatment with Lenabasum – Phase II

    Trial to Evaluate Efficacy and Safety of Lenabasum in Cystic Fibrosis

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