What Intestinal Diseases Lead to Transplantation?

The experts at UPMC Children’s Hospital of Pittsburgh treat a variety of pediatric intestinal diseases. The following diseases may require an intestine transplant. Learn more about these diseases by clicking the links below.

Short-gut Syndrome

• Necrotizing enterocolitis
• Intestinal atresia and stenosis
• Midgut volvulus
• Complicated gastroschisis
• Abdominal trauma
• Advanced Crohn’s disease
• Extensive surgical adhesions
• Gardener’s syndrome (familial polyposis)
• Desmoid tumor
• Mesenteric vascular thrombosis
• Radiation enteritis
• Massive intestinal polyposis

Defective Gastrointestinal Motility

• Hollow visceral myopathy
• Total intestinal aganglionosis
• Extensive visceral neuropathy
• Chronic intestinal pseudo-obstruction
• Hirschsprung’s disease

Impaired Enterocyte Absorptive Function

• Microvillus Inclusion Disease (MID)
• Selective autoimmune enteropathy
• Tufting enteropathy