Pediatric Cardiology and Heart Institute

Kids who are born with a heart defect or acquire heart disease, have access to complete care at Children's.

The experts at the Heart Institute at UPMC Children's Hospital of Pittsburgh treat all types of heart problems.

We use the latest technology and provide heart care from before birth to adulthood.

Heart Tests and Exams for Your Child

Our heart care team offers:

Top-Rated for Pediatric Cardiothoracic Surgery

The cardiothoracic (CT) surgery program at Children's cares for children with all types of heart and blood vessel diseases.

Our program is in a tie with one other program in the nation on having the lowest four-year surgical death rate.

Based on the latest data from the Society of Thoracic Surgeons:

  • The average national death rate for all children's heart and vascular programs was 3.4 percent.
  • Children's ranks among the top high-volume programs in the country, with a mortality rate of 1.5 percent.



Clinical Studies

  • Cardiology

    UPMC Children's Hospital of Pittsburgh
    4401 Penn Avenue
    Floor 3
    Pittsburgh, PA 15224
  • Children's North

    2599 Wexford Bayne Rd.
    Sewickley, PA 15143
  • Children's South

    205 Millers Run Rd.
    Bridgeville, PA 15017
  • Children's East

    4055 Monroeville Blvd.
    Building One
    Monroeville, PA 15146
  • UPMC Children's Specialty Care Center Cumberland

    Johnson Heights Medical Building
    625 Kent Ave.
    Suite 102
    Cumberland, MD 21502
  • UPMC Children's Specialty Care Center Hermitage

    UPMC Outpatient Center
    449 N. Hermitage Road
    Hermitage, PA 16148
  • UPMC Children's Specialty Care Center Johnstown

    865 Eisenhower Blvd.
    Johnstown, PA 15904
  • UPMC Children's Specialty Services in Lemoyne

    3 Walnut Street
    Suite 205
    Lemoyne, PA 17043
  • Altoona Regional Medical Center

    620 Howard Ave.
    Altoona, PA 16601
  • UPMC Children's Community Pediatrics – Butler

    100 Technology Dr.
    Suite 2
    Butler, PA 16001
  • Conemaugh Medical Center

    1086 Franklin Street
    Johnstown, PA 15905
  • Dubois Medical Arts Building

    145 Hospital Ave.
    Suite 102
    DuBois, PA 15801
  • UPMC Greensburg

    Stone Villa Professional Center
    660 Pellis Road
    Suite 202
    Greensburg, PA 15601
  • UPMC Hamot

    Hamot Heart Institute Diagnostic Center
    118 East 2nd Street
    First Floor
    Erie, PA 16507
  • Adults with Congenital Heart Disease Awaiting Cardiac Transplantation

    Late Outcomes and Survival in Adults with Congenital Heart Disease Awaiting Cardiac Transplantation II

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    Aortic Coarctation Treatment Comparison Study

    Comparison between Surgical vs. Balloon Angioplasty vs. Intravascular Stent Placement for Recurrent or Native Coarctation of the Aorta

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    Atrial Switch Procedure Database Study

    Atrial Switch Database for Transposition of Great Arteries

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    Cardiac Biomarkers Generated in Children and Adolescents when Exercising

    Effect of Exercise on Serum Cardiac Biomarker Levels in Children and Adolescents

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    Heart Muscle Cell Growth Study for Infants with Complex Congenital Heart Disease

    Mechanistic Clinical Trial of Beta-blocker Administration for Reactivating Cardiomyocyte Division in Tetralogy of Fallot

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    Kawasaki Disease/COVID-19 Research Registry

    The Association of Kawasaki Disease and COVID-19 with Cardiac Complications: A Focused Sub-study of the International Kawasaki Disease Registry (IKDR)

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    Neurocognitive Impact of Surgical Re-intervention for Congenital Heart Disease

    Neurocognitive Function of Adolescents and Young Adults with Repaired Complex Congenital Heart Disease After Recent Cardiac Re-Interventions: A Pilot Study

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    Patent Ductus Arteriosus Closure with MVP™ Plug: A Retrospective Review

    Retrospective Review of PDA Closure with Medtronic MVP™ Micro Vascular Plug in Patients Weighing Less Than Two Kilograms

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    Pediatric & Congenital Heart Disease with Heart Failure – Treatment with Advanced Cardiac Therapies: The ACTION Project

    Advanced Cardiac Therapies Improving Outcomes Network (ACTION) to Improve the Health of Pediatric and Congenital Heart Disease Patients with Heart Failure

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    Pediatric Heart Transplant Immunosuppressive Therapy Comparing Two Regimens: The TEAMMATE Study – Phase III

    Clinical Trial Comparing Everolimus and Low-Dose Tacrolimus to Tacrolimus and Mycophenalate Mofetil at 6 Months Post Heart Transplant to Prevent Long-Term Complications after Pediatric Heart Transplantation

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    Pregnancy & Congenital Heart Disease

    Prognosis of Pregnant Women with Congenital Heart Disease

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    Pulmonary Arteriovenous Malformation Causes Study

    ALK1 Signaling in Development of Superior Cavopulmonary Anastomosis-Associated Pulmonary Arteriovenous Malformations

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    Pulmonary Blood Flow Treatment with Stent versus Shunt

    Ductal Stenting vs. Surgical Shunt for Infants with Duct Dependent Pulmonary Blood Flow

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    Pulmonary Valve Stenosis Identification Before Birth

    Fetal Predictors of Pulmonary Valve Stenosis and Determining Post-Delivery Management

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    Pulmonary Vein Stenosis Study

    Pulmonary Vein Stenosis: Disease Mechanisms and Outcomes

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    Supraventricular Tachycardia Management – A Treatment Comparison Study

    Calcium Channel Blockers versus Beta Blockers in the Chronic Management of SVT in Pediatric Subjects without Pre-excitation Syndrome or Hemodynamically Significant Heart Disease

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    Transplant EBV Disease Study

    Transplant Epstein-Barr Virus (EBV) Disease – Pathogenesis and Immunotherapy

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