Emergency Medicine Research

Research in the Division of Pediatric Emergency Medicine at UPMC Children’s Hospital of Pittsburgh is helping set new standards of care, both for first responders who transport infants and children in life-threatening situations and for the emergency department medical teams that treat them.

The division has a robust clinical research infrastructure including a dedicated research office adjacent to the Emergency Department. Our clinical researchers are led by Robert W. Hickey, MD, and supported by four registered nurses and four research assistants. In recent years, the division’s clinical research team has annually enrolled, on average, about 1,200 children in various studies.

Our key studies are funded by the National Institutes of Health (NIH) and the Centers for Disease Control and Prevention, and the division is a member of the prestigious Pediatric Emergency Care Applied Research Network, a consortium of 18 children’s hospitals performing large-scale pediatric emergency medicine research studies funded by the federal government.

Recent clinical research programs by the division have examined treatment of urinary tract infections, treatment of concussion, management of young febrile infants, diagnosis of pneumonia, identification of cervical spine injuries, non-invasive diagnosis of strep throat, and prevalence of influenza, to name a few.

With NIH support, basic and translational research by the Division of Pediatric Emergency Medicine is led by Mioara Manole, MD, FAAP, and includes investigations into pediatric asphyxial cardiac arrest, adult cardiac arrest, and pediatric and adult traumatic brain injury. Our state-of-the-art translational laboratory is also part of the internationally recognized Safar Center for Resuscitation Research.

Clinical Studies

Researchers

Acute Gastroenteritis (AGE) and Acute Respiratory Illness (ARI) in Children

Enhanced Active Surveillance of Pediatric Infectious Disease and Vaccine by the New Vaccine Surveillance Network

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Blood Clotting in Traumatic Injury

Mechanism of Trauma-Induced Coagulopathy in Pediatric Patients

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Influenza Vaccine Effectiveness: The Flu VE Study

U.S. Flu Vaccine Effectiveness Network: Pittsburgh

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Lyme Disease Diagnosis Study

Novel Diagnostics for Lyme Disease

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Neck Injury Evaluation: The CSPINE Study

Development and Testing of a Pediatric Cervical Spine Injury Risk Assessment Tool

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Pediatric Concussion Treatment via Active Injury Management

Active Injury Management (AIM) after Pediatric Concussion

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Respiratory Illness Diagnostic Test: The RADICAL Study

Rapid Diagnostic Test for the Categorization of Acute Respiratory Illness

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Strep Throat Testing Device Study

Pilot Study of Strepic® Device for the Diagnosis of Group A Streptococcal (GAS) Pharyngitis

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Additional Researchers

Martin G. Hellman