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A research assistant professor of pediatrics at the University of Pittsburgh, Nadia Boutaoui, PhD, has dedicated her research focus to asthma genetics and epigenetics. Having implemented and managed genome-wide genotyping and methylation platforms for multiple studies, she is interested in using genetics and epigenetics tools to understand the effect of nutrition and environmental exposures on respiratory diseases such asthma. She has established a quality control pipeline for Genome Wide Association Studies (GWAS). She and colleagues have identified FAM13A as a chronic obstructive pulmonary disease (COPD) susceptibility locus and shown that variable DNA methylation is associated with COPD and lung function. They also reported that exposure to violence is associated with ADCYAP1R1 (a gene implicated in post-traumatic stress disorder) methylation and asthma in Puerto Rican children, and that high child stress and an ADCYAP1R1 SNP are associated with reduced bronchodilator response in children with asthma
See Dr. Boutaoui’s Full Bio
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One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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