Sameer Agnihotri, PhD

Sameer Agnihotri, PhD

Assistant Professor, Division of Neurosurgery, Department of Pediatrics, University of Pittsburgh School of Medicine
Director, Brain Tumor Biology and Therapy Lab, University of Pittsburgh Department of Neurological Surgery
Scholar, Richard King Mellon Institute for Pediatric Research, UPMC Children’s Hospital of Pittsburgh


Graduate School: 2011 PhD, Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

2016 Fellowship, Hospital for Sick Children, Toronto
2016 Fellowship, Princess Margaret Cancer Centre, Toronto

Research Interests

Recognized for his work and expertise on pediatric brain tumors, Sameer Agnihotri, PhD, leads a laboratory focused on brain tumor biology and therapy. His research interests include using next-generation sequencing technology to identify and validate driver alterations of various high-grade gliomas with a focus on diffuse intrinsic pontine glioma and non-histone mutated receptor tyrosine kinase glioblastoma. His laboratory investigates the metabolic dependencies of brain tumors to determine if they can provide therapeutic vulnerabilities. It also uses genomic and metabolic information to build pre-clinical models for testing novel therapies and works closely with clinical teams to apply the models in the initiation of early phase clinical trials. Dr. Agnihotri is a 2022 recipient of the prestigious Distinguished Scientist Award grant from the Sontag Foundation, which is being applied to further his research on brain tumors.

View Dr. Agnihotri's full list of publications from PubMed.
View Dr. Agnihotri’s lab website.