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This multi-center study is investigating long-term effects of the Viaskin® Peanut patch for young children with peanut hypersensitivity. The research is designed specifically for children who were enrolled in a prior year-long protocol – the EPITOPE study. Through this extension study, participants will have used Viaskin Peanut for a total of three years. The patch contains a 250 microgram peanut protein antigen used to desensitize patients against allergic reactions through a process called epicutaneous immunotherapy. Researchers will test the theory that longer periods of treatment result in more efficient desensitization and greater tolerance of peanuts..
The study is enrolling children ages 2 through 4 who have been diagnosed with a peanut allergy and who participated in the EPITOPE study.
Boys and Girls: Ages 2 through 4
Participants in the original EPITOPE study used either Viaskin Peanut or a placebo patch. Those who received Viaskin Peanut will continue to use the product for 2 more years. Those who received the placebo patch will use Viaskin Peanut for 3 years. After the initial study visit, participants will be seen about 4 times a year, during which they will receive physical examinations and be tested for peanut tolerance.
Visits: 9 to 12 depending on length of enrollment
Duration: 2 years and 1 month for those who received Viaskin Peanut, and 3 years and 1 month for those who received a placebo patch in the EPITOPE study
Study Description at National Institutes of Health
Allergy and Immunology Research
Deborah Albright, MD
For more information about the study, please contact:
Susan Richey, RN
Clinical Research Coordinator
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UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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