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The purpose of this multi-center research study is to evaluate the effects of glecaprevir and pibrentasvir in pediatric patients with chronic hepatitis C virus (HCV) infection. Researchers will be measuring the pharmacokinetics – how the body processes the drug combination – as well as effectiveness in treating chronic HCV infection.
Subject to certain exclusion criteria, this study is accepting patients of both genders ages 3 through 17 with chronic HCV genotype 1-6 infection.
Boys and Girls: Ages 3 through 17
Potential participants have a screening visit that includes a physical exam, blood work, and other tests to determine eligibility. If eligible, participants will take the study medication once daily for 8, 12, or 16 weeks, depending on their type of HCV infection and other factors. During treatment, participants will return to the clinic for blood tests and other monitoring. After treatment completes, participants will return to the study site for additional monitoring and blood work for about 3 years.
Visits: 11 to 13
Duration: About 3 years
Study Description at National Institutes of Health
Robert H. Squires, Jr. MD
For more information about the study or enrollment, please contact:
Adam D. Kufen, RN, BS, CCRC, MBA
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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