Read the Latest
Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #6 Nationally by U.S. News & World Report.
The goal of this multicenter trial by the Children’s Oncology Group is to determine the effectiveness of chemotherapy and a type of radiation therapy called whole ventricular irradiation (WVI) when used against newly diagnosed central nervous system tumors. Patients participating in this study will be given standard-of-care chemotherapy with WVI and a radiation treatment to the primary site of disease. Study doctors would like to see if giving WVI, a smaller dose of radiation, will be as effective as the radiation treatments used in previous studies.
Subject to certain exclusion criteria, this study is open to patients of both genders ages 3 to 21, who have been diagnosed as having central nervous system germinoma or NGGCT.
Males and Females: Ages 3 to 21
For patients with germinoma and NGGCT, therapy starts with induction chemotherapy in 21-day cycles – 4 cycles for patients with germinoma, 6 cycles for those with NGGCT. Following induction chemotherapy, there will be an evaluation to determine whether second-look surgery is required or if the patient can proceed directly to radiation therapy. The amount of radiation therapy may vary from 4 to 5 weeks and may be at a reduced level or standard level. Radiation therapy may also follow second-look surgery.
Visits: Same number as required with standard therapy
Duration: Approximately 4 to 60 months depending on outcomes
Children’s Oncology Group (ACNS1123)
National Cancer Institute
Study Description at National Institutes of Health
Cancer and Blood Disorder Research
Jean Tersak, MD
For more information about the study or enrollment, please contact:
Research Coordinator Angela Connelly, RN, BSN
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.