Your health can’t wait. Learn how we’re making our facilities safer and schedule your care now.
Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #9 Nationally by U.S. News & World Report.
Through this multi-center Pediatric Brain Tumor Consortium investigation, researchers are studying the effects of panobinostat in young patients with diffuse intrinsic pontine glioma (DIPG), a type of inoperable brain stem tumor. Investigators will determine how the body processes the study drug and optimal dosage levels for future studies. Lab tests and other studies have demonstrated that panobinostat can inhibit certain cellular activities that promote tumor growth.
Subject to certain exclusion criteria, this study is enrolling pediatric patients who have been diagnosed with progressive DIPG.
Males and Females: Ages 2 to 21
Participants will take the study drug in capsule form once a day, 3 times a week for 3 weeks followed by a week of not taking the drug. This 4-week period is called a cycle. Barring adverse events, participants may remain in the study for up to 26 cycles. Physical examinations will be given throughout the study, with imaging, blood work, and other tests done at prescribed intervals.
Visits: About 40
Duration: Up to 2 years
National Cancer Institute
Pediatric Brain Tumor Consortium (PBTC-047)
Study Description at the National Institutes of Health
Cancer and Blood Disorder Research
Alberto Broniscer, MD
For more information about the study or enrollment, please contact:
Research Coordinator Sharon Dibridge
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.