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Through this multi-center Children’s Oncology Group study, researchers are evaluating the effects of the drug eribulin mesylate provided to participants suffering from certain types of cancers that have returned or did not respond to standard treatments, specifically rhabdomyosarcoma, non-rhabdomyosarcoma soft tissue sarcoma, and Ewing sarcoma.
Subject to certain exclusion criteria, this study is accepting patients, ages 12 months to 18 years, with confirmed rhabdomyosarcoma, non-rhabdomyosarcoma soft tissue sarcoma, or Ewing sarcoma. The age range for participants is 12 months to 18 years.
Males and Females: Ages 12 months to 18 years
In 3-week cycles, participants will take the study drug via intravenous infusion on days 1 and 8. During visits for infusions, participants will receive examinations, testing and blood draws. Imaging will also be done at certain intervals. Participants will receive up to 6 cycles of eribulin mesylate, however those who receive a clinical benefit may continue on the study treatment while the study remains active.
Visits: 2 visits for infusions in each 21-day cycle
Duration: 18 weeks (6, 3-week cycles), and possibly longer for patients who benefit from treatment
Children’s Oncology Group (ADVL1722)
National Cancer Institute
Study Description at National Institutes of Health
Cancer and Blood Disorder Research
Andrew Bukowinski, MD, MS
For more information about the study or enrollment, please contact:
Andrew Bukowinski, MD, MS
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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