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This study assesses the long-term functional outcome of survivors from neonatal encephalopathy treated with either head cooling or with conventional care. Although it only occurs in approximately 3 out of 1000 full-term births, moderate to severe neonatal encephalopathy continues to be an important cause of acute neurologic injury at birth and subsequent long-term disability. A scientific study of head-cooling known as the “Cool Cap trial,” during the years 1999-2003 suggested that hypothermia was protective in the group of infants with moderately severe encephalopathy. However, one of the major factors limiting clinical adoption of head-cooling hypothermia was the lack of long-term follow-up.
Children, ages 7 and 8, of both genders who participated as neonates in the Cool Cap study at either Children’s Hospital of Pittsburgh of UPMC or Magee-Womens Hospital are eligible for participation.
Boys: Less than 7 days old
Girls: Less than 7 days old
The only requirement is a telephone interview of parents of previously enrolled children who survived. The special WeeFIM® questionnaire determines the child’s current level of performance on a set of skills basic for daily functioning.
Visits: Not applicable
Duration: Not applicable
Olympic Medical subsidiary of Natus Medical, Inc.
Study description at National Institutes of Health
Toby Debra Yanowitz, MD
Toby Debra Yanowitz, MD
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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