COVID-19 Vaccine Information and Updates
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Through this multi-center study, researchers are investigating the use of benralizumab for safe treatment of severe uncontrolled asthmas in children. Researchers believe that benralizumab may help to prevent a signal (a protein made by the body called interleukin-5) that allows the formation and activation of eosinophils, a type of white blood cell that, when activated, can lead to uncontrolled asthma in some people.
Subject to exclusion criteria, this study is accepting participants ages 6 through 11 who have been diagnosed with child has severe uncontrolled asthma.
Boys and Girls: Ages 6 through 11
Following a screening period, participants will receive the study drug by injection 4 times over 16 weeks, during which time researchers will study its effects and how the body processes it. Participants will continue to receive the drug 3 more times over an additional 32 weeks (total 48 weeks), while researchers study longer-term effects. A follow-up visit will occur within 4 weeks after the final dose of the study drug.
Duration: 56 weeks from screening to follow-up (1 year, 1 month)
Study Description at National Institutes of Health
Allergy and Immunology Research
Allyson Larkin, MD
For more information about the study or enrollment, please contact:
Linette Milkovich, RN
Clinical Research Coordinator Susan Richey, RN
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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