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This multi-center study evaluates the effectiveness of sugammadex following a surgical procedure to reverse the effects of a muscle relaxant used during surgery. Researchers believe that sugammadex, also known by the trade name Bridion™, may be superior to the conventional drug used to reverse moderate neuromuscular blocking as measured by time to neuromuscular recovery.
Subject to certain exclusion criteria, children newborn through ages 2 who require a neuromuscular blocking agent for a non-emergency surgical procedure are eligible for this study.
Boys and Girls: Up to Age 2
Participants will be given a muscle relaxant drug at the beginning of surgery and will receive sugammadex at a specified dosage at the end of the procedure. Blood testing will be done to evaluate how the body processes the study drug on some patients.
Visits: Requires hospitalization for surgery and a follow-up visit and phone call in the post-operative period
Duration: 28 days
Merck Sharp & Dohme
Study Description at National Institutes of Health
Daniela Damian, MD
For more information about the study or enrollment, please contact:
Denise McCarthy RN, BSN, CRC
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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