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This research initiative of the Pediatric Blood and Marrow Transplant Consortium evaluates next-generation genetic sequencing techniques to identify potential sources of lung infection in respiratory secretions of patients who have had hematopoietic stem cell transplant (HSCT). Sources of infection may include bacteria, viruses, fungi, and other organisms.
Subject to certain exclusion criteria, this study is enrolling patients who have a history of HSCT and are planned to undergo a clinically indicated collection of a lower respiratory specimen due to a suspected lung infection or inflammation.
Males and Females: Up to 21 years of age
Respiratory secretions will be collected from the lower lung via bronchoalveolar lavage, tracheal aspirate, or other means. Other sampling – nasal swab, urine, and blood sample – may also be done.
Visits: None beyond normal clinical care for this condition
Duration: Not applicable
Pediatric Blood and Marrow Transplant Consortium (PBMTC SUP1601)
Study Description at the National Institutes of Health
Blood and Marrow Transplantation and Cellular Therapies Research
Jessie Barnum, MD
For more information about the study or enrollment, please contact:
Shawna McIntyre, Clinical Research Supervisor
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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