Cardiac Biomarkers Generated in Children and Adolescents when Exercising

Effect of Exercise on Serum Cardiac Biomarker Levels in Children and Adolescents

Protocol Description

This prospective study evaluates if cardiac biomarkers, such as troponin levels, can rise to the detectable range in healthy children and adolescents after short bursts of exercise. This will provide useful information to pediatric cardiologists and emergency medicine doctors who are often confronted with a mildly positive troponin level – which can be an indicator of cardiac muscle damage – in a patient who recently exercised and is perhaps complaining of chest pain but is otherwise asymptomatic. Studies have shown that strenuous exercise in adults can lead to troponin elevations, but this has not been evaluated in less strenuous exercise in pediatric patients.

Eligibility Criteria

Subject to certain exclusion criteria, researchers are accepting healthy children and adolescents, aged 7 through 17 years, who can participate in the study exercise regimen.
Boys and Girls: Ages 7 through 17


Researchers will conduct electrocardiograms and collect and blood samples to monitor cardiac biomarker levels from healthy pediatric patients before and after exercise.
Visits: 1
Duration: 5 hours

Status: Open to Enrollment

Additional Information

Cardiology Research

Primary Investigator

Tyler Harris, MD

Contact Information

For more information about the study, please contact:
Cullen Wenzler, Clinical Research Coordinator