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This study is being done to determine the safety and effectiveness of dexmedetomidine on children who are having a medical procedure or surgery to treat an illness, or a testing procedure to diagnose an illness, either of which requires sedation. The medicine, which will be provided as a calming agent before a procedure, is approved for adults, but is not yet approved for children.
Subject to certain exclusion criteria, the study is open to patients in the Cardiac Intensive Care Unit who are having a medical procedure that requires a sedative and is expected to take more than 30 minutes.
Boys and Girls: Ages 1 through 16
The study drug will be provided via continuous infusion at a dosage based on patient size. Vital sign monitoring will begin prior to testing, treatment or surgery, and will continue during and after the procedure until the patient is released. Follow-up will be done after 24 hours and again after 30 days.
Visits: Up to 3
Duration: Up to 45 days
Study Description at National Institutes of Health
For information, please contact:
Kelli Shepler, CRC
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.