Neurocognitive Impact of Surgical Re-intervention for Congenital Heart Disease

Neurocognitive Function of Adolescents and Young Adults with Repaired Complex Congenital Heart Disease After Recent Cardiac Re-Interventions: A Pilot Study

Protocol Description

Through this multi-center study, researchers are investigating the impact on neurocognitive function of a type of heart surgery on people with congenital heart disease who required open heart surgery as an infant.

Eligibility Criteria

Subject to certain exclusion criteria, people with congenital heart disease that required an open-heart operation before the age of 1 and who are now scheduled to undergo a right ventricular outflow tract re-intervention are eligible for this study.
Males and Females: Ages 13 to 30


Participants will meet with a member of the research staff upon enrollment and answer a series of questionnaires related to health, quality of life, and brain function. Following surgery, the research team will review the patient’s medical record. At 3 months after surgery, participants will be asked to complete two surveys by mail. The surveys will be repeated by mail at the 1-year interval. The research team will also screen participants for signs of depression in a follow-up phone call.
Visits: 1, which can be done at the time of a regularly scheduled visit
Duration: 1 year

Status: Enrolls from Current Patient Cases

Source(s) of Support

University of Michigan

Primary Investigator

Bryan Goldstein, MD

Contact Information

For more information about the study, please contact:
Cullen Wenzler, Research Coordinator