Pulmonary Atresia Treatment in Neonates via Pulmonary Valve Perforation: A Retrospective Review

Pulmonary Valve Perforation Study

Protocol Description

This retrospective review examines outcomes of using radio frequency (RF) or chronic total occlusion (CTO) devices to open the pulmonary valves of patients who had pulmonary atresia with an intact ventricular septum (PA/IVS) between 2007 and 2019. Pulmonary atresia is a rare condition in which the pulmonary valve that controls blood flow to the lungs, is blocked. RF perforation and CTO device perforation of the valve are techniques done via minimally invasive heart catheterization.

Eligibility Criteria

Patients with a diagnosis of PA/IVS who were referred to the Cardiac Catheterization Laboratory at UPMC Children’s Hospital of Pittsburgh for treatment from 2007 through 2019 for attempted perforation of their atretic pulmonary valve will be included in the review.
Males and Females: Neonates


There are no requirements for participants. Clinical data is extracted from the medical record for review and analysis.
Visits: None required
Duration: Not applicable

Status: Enrolls from Current Patient Cases

Source(s) of Support

University of Michigan

Primary Investigator

Sara Trucco, MD

Contact Information

For more information about the study, please contact:
Cullen Wenzler, Clinical Research Coordinator