Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #8 Nationally by U.S. News & World Report.
This multi-center study is investigating the effectiveness of the drug crinecerfont in reducing daily glucocorticoid dose and adrenal-related hormone levels, as well as other clinical factors related to glucocorticoid use (such as body weight and insulin resistance) in adults with classic congenital adrenal hyperplasia (CAH), a genetic disorder affecting hormone production by the adrenal glands.
Subject to certain exclusion criteria, this study is enrolling participants who are at least 18 years of age and who have been diagnosed with classic CAH that is being treated with a daily dose of glucocorticoid.
Males and Females: Ages 18 and older
The study has five stages spanning 19 months, including: a screening period, three study-drug dosing periods and a follow-up period. In the first dosing period, participants will be assigned to take crinecerfont or a placebo twice a day for about six months. In the subsequent dosing stages, lasting up to a year, participants will take crinecerfont at specified dosing levels. Throughout the study, various physical examinations and tests will be given to monitor participants’ health and effects of the study drug, and to adjust participants’ glucocorticoid dosage.
Duration: 19 months
Study Description at National Institutes of Health
Endocrinology, Diabetes and Metabolism Research
Selma Witchel, MD
For more information about the study or enrollment, please contact:
Clinical Research Coordinator Vibha Chauhan, PhD, CCRP, CCRC
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With MyCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.