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For more information about research, please call our main office at 412-692-6438.
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The goal of this multi-center research study is to determine the effectiveness of the oral antibiotic azithromycin in treating preschoolers experiencing acute wheezing episodes.
Children, ages 18 through 59 months, being seen in the Emergency Department for an acute wheezing episode, are eligible for participation in this study. Boys and Girls: Ages 18 months through 4 years (59 months)
Participants will be given a physical examination that will include a cheek and nasal swab to collect biologic samples. Through randomized selection, participants will be provided a 5-day prescription of either azithromycin or a placebo. Parents/guardians will provide information about the child’s symptoms during the Emergency Department visit and will complete a daily diary about the child’s symptoms during drug therapy. The research team will follow up with the parent/guardian on day 8. Some children will be randomly selected for follow-up visits for additional examinations and testing. Visits: 1 to 3, depending on whether participating in follow-up visits Duration: 8 to 21 days, depending on whether participating in follow-up visits
National Heart, Lung, and Blood Institute
Study Description at National Institutes of Health Asthma and Wheezing Emergency Medicine Research
Melissa Tavarez, MD
For more information about the study or enrollment, please contact: Research Coordinator 412-692-8380
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh One Children’s Hospital Way 4401 Penn Ave. Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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