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This study, funded by the National Institutes of Health (NIH), will help determine whether children ages 6 to 23 months diagnosed with an ear infection (AOM) can be effectively treated with antibiotics for 5 days rather than 10. A shorter treatment course may be beneficial in 1) reducing the likelihood of side effects, the most common being diaper rash and diarrhea, and 2) reducing antibiotic resistance, which occurs when bacteria change in a way that makes it harder to be killed by antibiotics.
Children enrolled in the study will have careful monitoring and follow-up for ear infections. There are no charges for visits or study medications. The clinical team is available by phone, 24 hours a day, and will see study participants whenever parents have concerns that the child may have another ear infection.
This study is open to children, ages 6 through 23 months, who have been diagnosed with AOM during the respiratory season (October 1 through March 31), for whom treatment has not yet been initiated.
National Institute of Allergy and Infectious Diseases, NIH
Study description at National Institutes of Health
Alejandro Hoberman, MD
For information or to enroll, please contact: 412-999-EARS (3277)
Consent Form For This Study (PDF)
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh One Children’s Hospital Way 4401 Penn Ave. Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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