COVID-19 Vaccine Information and Updates
Read the Latest
Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #9 Nationally by U.S. News & World Report.
This study, funded by the National Institutes of Health (NIH), will help determine whether children ages 6 to 35 months diagnosed with recurrent ear infections (rAOM) (3 infections in 6 months or 4 in 12 months, with at least 1 episode in the past 6 months) need to have ventilating tubes placed in the ear drum or whether they can be effectively treated with antibiotics for each ear infection. There are pros and cons of each of these two treatment modalities.
May reduce by 1 or 1.5 the average number of ear infections each year
Are given with each ear infections: twice a day for 10 days
Parents will see pus in the ear canal when their child has an infection
Parents will know their child has an ear infection by the usual symptoms
In most instances we will treat ear infections with antibiotic ear drops instead of antibiotics by mouth, thus decreasing the likelihood that germs that cause the ear infection to become resistant.
May increase the likelihood of germs becoming resistant and not being killed by the antibiotic
The surgical procedure requires anesthesia which is generally not recommended in children under 3 years of age
May have side effects such as allergy, diarrhea, or a yeast infection
May become blocked, fall out of place (behind the ear drum into the middle ear or outside) or leave scars or persistent perforations of the ear drum
There are 2 phases to this program, a screening phase and a randomization phase. During the screening phase, we will identify a group of children who are at risk for recurrent ear infections, follow them over time and have our team of experts examine his/her ears to confirm that your child had at least 1 ear infection that we have seen. Children who actually go on to have rAOM will be offered to participate in the second part of the study, in which we will try to determine which children are most likely to benefit from ear tubes, and will be carefully followed for 2 years.
Children enrolled in our program will have careful monitoring and follow-up for ear infections. There will be no charges for study related visits. The clinical team is available by phone, 24 hours a day, and will see study participants whenever you have concerns that your child may have another ear infection.
Part 1: In the screening phase, we will obtain informed consent from the parent(s) of children who have risk factor(s) for recurrent ear infections, and follow them prospectively.
Part 2: In the randomization phase, children aged 6 to 35 months who meet inclusion criteria for rAOM will be randomized to have ventilating tubes which will be placed within 2 weeks or treated with oral antibiotics for future ear infections and have tubes placed later on if they continue to have recurrent ear infections.
Part 1: Screening Phase
Part 2: Randomization Phase
Alejandro Hoberman, MD
For more information or to register to learn more, call 412-999-EARS (3277)
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.