Children's Hospital is part of the UPMC family.
Our Sites
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #6 Nationally by U.S. News & World Report.
The purpose of this study is to find out if a single injection of an investigational RSV monoclonal antibody (MK-1654) can prevent RSV infection in infants. MK-1654 is a fully human monoclonal antibody with long-half life that targets the RSV F protein. RSV infection is a common infection among infants less than 2 years of age. RSV can cause cold like symptoms with fever and in some children, it can cause lung infection (bronchiolitis) which can result in breathing difficulty and low oxygen level in the blood and dehydration. Currently there are no approved treatments for prevention of RSV infection in healthy infants. Existing preventive treatment (Palivizumab, Synagis) is targeted towards preterm infants born before 29 weeks of gestation or preterm infants with underlying heart or lung problems.
This study will enroll healthy Infants with a gestational age of ≥29 weeks born after January 1, 2022, who do not qualify for Synagis (Palivizumab).
Participants will complete 6 study visits over 12 months. Study assessments will include medical history, physical exam, blood tests, buccal and nasopharyngeal swabs. In addition, Infants in the study will be closely monitored for respiratory illness through weekly phone calls during the first 6 months (RSV season). Children with signs and symptoms of possible RSV infection will undergo a nasopharyngeal swab for RSV test.
Visits: 6 Duration: 12 months Number of blood draw: 3 Buccal swab: 1 time, optional Nasopharyngeal swab: if there are symptoms and signs of respiratory infection
Merck
Kumaravel Rajkumar, MD, MS
To get started, please contact Dr. Kumaravel Rajakumar: email: rajakumark@upmc.edu Mr. Matt Lee (Study Coordinator): phone: 412-692-7806, email: leemc5@upmc.edu
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh One Children’s Hospital Way 4401 Penn Ave. Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.