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This study is looking at the viruses and bacteria that are currently causing ear infections (AOM), including resistant bacteria. This research may help understand how infections are preventable by vaccines and enable development of adequate guidelines for treatment and vaccination.
Children, with ear infections, enrolled in the study will have careful monitoring and follow-up for their ear infection through resolution of the episode. Children, with cold symptoms, enrolled in the study will have the benefit of close monitoring of their symptoms. Children, who have tympanocentesis, may experience relief from pain following fluid collection since this relieves the pressure behind the ear drum and helps the doctors decide what is the best antibiotic for your child. There are no charges for visits and adequate antibiotic treatment for the ear infection will be prescribed. The study team is available by phone; 24 hours a day.
Subject to certain exclusion criteria. This study is open to children ages 6-35 months, who have been diagnosed with an ear infection or have had cold symptoms for 72 hours or less.
This study will have two visits; an enrollment visit and a follow-up visit. We will also see your child as needed if he/she is not feeling well between study visits. For all children enrolled in the study, we will perform an ear exam, take a picture of the ear drum and collect a nasal swab. We will also ask you to complete a daily diary of symptoms. Some children with more severe infections as evidenced by bulging eardrums and symptoms will have a procedure known as tympanocentesis. Tympanocentesis is done by making a small opening in the eardrum with a needle and drain the pus to relieve pressure immediately. We may ask some participants for a urine and/or blood sample.
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
Alejandro Hoberman, MD
Judith Martin, MD
For additional information or to enroll, please contact 412-692-7382.
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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