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This Pediatric Brain Tumor Research Consortium trial is studying how well peginterferon alfa-2b (PEGIntron) works in treating younger patients with a craniopharyngioma that is recurrent or cannot be removed by surgery. PEGIntron may interfere with the growth of tumor cells and slow the growth of craniopharyngioma.
Subject to certain exclusion criteria, this study is open to males and females, ages 18 months to 25 years old, who have craniopharyngioma that is recurrent or cannot be surgically removed.
Males and Females: Ages 18 months to 25 years
Following an initial physical exam, participants will receive PEGIntron via injection at home once a week for each week of a 6-week course. This will be repeated for up to 18 courses. At specific intervals, researchers will require other tests, including blood and urine tests, ophthalmology evaluations and MRI scans of the brain.
Duration: Approximately 2 years
Pediatric Brain Tumor Consortium (Study PBTC-039)
National Cancer Institute
Study Description at National Institutes of Health
A. Kim Ritchey, MD
For more information about the study or enrollment, please contact:
Research Coordinator Angela Connelly, RN, BSN
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UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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