COVID-19 Information Read the Latest
Children's Hospital is part of the UPMC family.
Our Sites
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #6 Nationally by U.S. News & World Report.
Through this Children's Oncology Group (COG) study, researchers are investigating whether they can improve the treatment for young people with high-risk neuroblastoma by adding either 131I- Metaiodobenzylguanidine (131I-MIBG) or lorlatinib to standard chemotherapy. Lorlatinib will be used specifically with patients whose tumors have shown a change in a gene called ALK.
Subject to certain exclusion criteria, this study is enrolling patients ages 1 through 30 years at the time of their diagnosis with a high-risk neuroblastoma. Males and Females: Ages 1 through 30 years
Once a determination is made about their ALK gene, participants will be placed in a part of the study that compares treatment using 131I-MIGB to treatment via standard COG-recommended therapy (if no change in the gene); or treatment using Lorlatinib compared to standard COG-recommended therapy (if the gene has changed). Whether participants receive standard therapy or treatment with an experimental drug is determined by randomization. Visits: Number varies by treatment group. Duration: Varies by treatment group and will be either about 1-1/2 years or about 2-1/2 years for most participants.
Children’s Oncology Group (ANBL1531) National Cancer Institute
Study Description at the National Institutes of Health Cancer and Blood Disorder Research
Jean M. Tersak, MD
For more information about the study or enrollment, please contact the UPMC Children’s Hospital of Pittsburgh Hematology-Oncology research team, at: HOCHPPhaseI-II@upmc.edu
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh One Children’s Hospital Way 4401 Penn Ave. Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.