COVID-19 Information Read the Latest
Children's Hospital is part of the UPMC family.
Our Sites
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #9 Nationally by U.S. News & World Report.
This multicenter trial by the Children’s Oncology Group studies how well combination chemotherapy with or without ganitumab works in treating patients with newly diagnosed Ewing sarcoma that has spread to other parts of the body. Investigators believe that monoclonal antibodies, such as ganitumab, may block tumor growth in different ways by targeting certain cells. Ganitumab has been shown activity against Ewing sarcoma in both laboratory studies and prior clinical trials involving adults.
Subject to certain exclusion criteria, this study is accepting patients of both genders up to age 50, who have been newly diagnosed with Ewing sarcoma that has spread to other parts of the body. Males and Females: Up to age 50
Study participants will be randomly assigned to either receive standard combination chemotherapy for their condition or chemotherapy that includes ganitumab. For both, the treatment plan involves induction therapy (12 weeks), local control (surgery, irradiation or both), consolidation therapy (16 weeks), and metastatic site irradiation, if required. For patients receiving ganitumab, a 6-month maintenance regimen is added as a final stage. Visits: Same as required for standard care for this condition Duration: Approximately 9 to 15 months, depending on the study arm in which the patient is enrolled
Children’s Oncology Group (AEWS1221) National Cancer Institute
Study Description at National Institutes of Health Cancer and Blood Disorder Research
Jean Tersak, MD
For more information about the study or enrollment, please contact: 412-692-5055
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh One Children’s Hospital Way 4401 Penn Ave. Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.