Read the Latest
Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #9 Nationally by U.S. News & World Report.
Through this observational study, researchers will be collecting data about patients with urea cycle disorders (UCDs). This rare genetic condition leads to the accumulation of high levels of ammonia in the blood, which can lead to brain damage and other serious problems. The THRIVE study will track long-term outcomes in UCD patients by collecting observational and standard-of-care data. Analysis of the collected information may lead to insights that will help physicians learn more about treating people with the condition.
Subject to exclusion criteria, the study is accepting patients of both genders and of all ages who have a confirmed diagnosis of UCD.
Males and Females: All ages
With consent, physicians will provide medical history information, lab results and imaging reports about their enrolled patients. Parents/guardians or participants will complete health/quality-of-life questionnaires annually. These can be completed during routine doctor appointments or at home.
Visits: None beyond normal clinical care
Duration: Up to 10 years
Study Description at National Institutes of Health
Medical Genetics Research
Gerard Vockley, MD, PhD
For more information about the study or enrollment, please contact:
Maggie Hufton, BS
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.