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This study is being done to determine how many people of African or Caribbean descent with focal segmental glomerulosclerosis (FSGS) also have a genetic mutation on a gene called APOL1 (apolipoprotein L1). APOL1 is a naturally occurring gene that can be found in many organs of the body, including the kidneys. People with FSGS who have a mutation in their APOL1 gene have a higher risk of losing kidney function. This information may help us understand how to better help people with FSGS in the future.
Subject to certain exclusion criteria, this study is accepting participants, ages 18 through 60, who are of African or Caribbean descent who have biopsy-confirmed FSGS.
Males and Females: Ages 18 through 60
The study involves a single blood test and saliva sample.
Duration: Not applicable
Michael Moritz, MD
For more information about the study or enrollment, please contact:
Matt Butoryak, RN, CCRC
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.