Read the Latest
Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #6 Nationally by U.S. News & World Report.
In this study, researchers are evaluating a drug called DCR-PHXC, when given to children and adults with primary hyperoxaluria (PH) type 1 or type 2 (PH1 or PH2). More specifically, researchers will be studying how well the drug helps the liver to make less oxalate to reduce symptoms of PH. Lowering the levels of oxalate may have a positive effect on patients with PH because most of the symptoms from PH are due to the excessive amounts of oxalate accumulating in the body.
Subject to certain exclusion criteria, this study is accepting participants, ages 6 and older who have been diagnosed with PH1 or PH2.
Males and Females: Ages 6 and older
Participants will be randomly assigned to be given either the study drug or a placebo. The drug will be administered monthly by injection during study visits. There will be a total of 12 study visits for examinations, medical tests, and imaging.
Duration: Up to 7 months
Study Description at National Institutes of Health
Michael Moritz, MD
For more information about the study or enrollment, please contact:
Vibha Chauhan, PhD, CCRP, CCRC
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.