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The purpose of this study is to assess the effectiveness and side effects of the drug lorcaserin for people who have Dravet syndrome, a rare form of epilepsy that develops in infancy and causes convulsive seizures.
Subject to certain inclusion and exclusion criteria, this study is enrolling participants who are at least 2 years of age and who have been diagnosed with epilepsy with Dravet syndrome. Males and Females: Ages 2 and older
Following a four-week screening period, participants will be randomly assigned to a group that will take either lorcaserin or a placebo over a period of 14 weeks. Upon completion of this core phase, participants may participate in a 12-week extension period in which all participants will receive the study drug. From screening through treatment phases and final follow-up, participants will be seen by the study team at regular visits for physical examinations and medical testing. After the extension phase, participants may also be able to join an extended-access program to continue taking lorcaserin. Visits: 14 Duration: 34 weeks
Eisai
Study Description at National Institutes of Health Neurology Research
Yoshimi Sogawa, MD
For more information about the study or enrollment, please contact: Clinical Research Coordinator Dawn Thomas RN, MSN, CPN 412-692-5142 or 412-864-7442
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh One Children’s Hospital Way 4401 Penn Ave. Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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