Immune Markers in Normal Blood

Normal Human Subjects for Immune Assay Development

Protocol Description

This study is being done to determine the range of immune markers found in blood and blood cells in normal healthy individuals. Immune markers are proteins that determine our ability to resist harmful agents such as bacteria and other foreign substances. Because this natural process can also cause rejection of transplanted organs, it is important to study immune function. Researchers plan to use measurements obtained through the study as reference that can compare to measurements from individuals who have had transplants.

Eligibility Criteria

Subject to screening criteria, males and females ages 18 and up who have never had an organ transplant are eligible.
Males: Age 18 and older
Females: Age 18 and older


Participants will donate blood samples monthly as needed for the study. Samples can be drawn at the outpatient laboratory at Children’s Hospital of Pittsburgh of UPMC or other UPMC facility.
Visits: Up to 60
Duration: Up to 5 years

Status: Open for Enrollment

Source(s) of Support

Pediatric Transplantation Department, Children’s Hospital of Pittsburgh of UPMC

Primary Investigator

Rakesh Sindhi, MD

Contact Information

For more information, please contact:
Katie Hindes Kalata, BS, MPH
Kym Smith, BS