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The primary objective of this observational study is to track the progression of type 2 diabetes and related comorbidities and diabetic complications in participants of a prior research program as they transition to young adulthood. The original study, Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY), was a multi-center clinical trial to find the optimal approach to treatment of type 2 diabetes in children and adolescents that has already generated a wealth of information about the disease and its risk factors. With participants enrolled between 2004 and 2009, the original study ended in 2011. TODAY 2, Phase 2 (T2P2) is a longitudinal follow-up study of the TODAY cohort. Through T2P2, the progression of participants’ medical condition is being tracked along with other related information for 6 years, providing researchers with a longer-term perspective.
Only participants from the original TODAY study are eligible to participate in T2P2.
Males and Females: Ages dependent on age at enrollment in original TODAY study
During annual research visits at TODAY clinical centers, participants receive examinations that will track blood sugar control, cardiac function and vascular complications in the eyes, kidneys and nervous system, along with other medical and quality of life factors. Data is collected with respect to diabetes-related diagnoses and progression, comorbidities, and outcomes. Participants must continue receiving standard clinical care and management for diabetes and other medical conditions from their own self-selected primary care physicians or healthcare providers.
Visits: 6 annual visits and interim telephone contacts
Duration: 6 years
National Institute of Diabetes and Digestive and Kidney Diseases
National Institutes of Health (NIH)
Study Description at NIH
NIH Description of Original TODAY Study
Endocrinology, Diabetes and Metabolism Research
Silva A. Arslanian, MD
For more information about the study, please contact:
T2P2 study coordinator Samantha Cochenour, RN
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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